AcuteMyeloidLeukemia相关论文
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In the era of personalized medicine, information on molecular change at the gene level is important for patient care. Su......
目的:分析实体恶性肿瘤放化疗后发生急性髓系白血病（AML）患者的临床特征和生存。方法:回顾性分析2016年8月至2021年2月在中山大学附......
Arsenic-Containing Qinghuang Powder（青黄散） Is A Alternative Treatment for Elderly Acute Myeloid Leukem
Objective:To analyze the overall survival (OS) of elderly acute myeloid leukemia (AML) patients treated with oral arseni......
Effect of Compound Zhebei Granule（复方浙贝颗粒）Combined with Chemotherapy on Surface Markers of Leukemia S
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Synergism between Carnosic Acid and Arsenic Trioxide on Induction of Acute Myeloid Leukemia Cell Apo
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Effects of Compound Zhebei Granule(复方浙贝颗粒) Combined with Doxorubicin on Expression of Specific Surfa
Objective:To investigate the effects of Compound Zhebei Granule(复方浙贝颗粒, CZG) combined with doxorubicin hydrochlori......
目的 Venetoclax,an oral selective inhibitor of the anti-apoptotic protein BCL-2,showsencouraging anticancer activity and......
Promoter methylation of the candidate tumor suppressor gene TCF21 in myelodysplastic syndrome and ac
Objective Transcription factor 21(TCF21)has been identified as a candidate tumor suppressor gene epigenetically inactiva......
High doses of daunorubicin during induction therapy of newly diagnosed acute myeloid leukemia:a syst
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Objective Acute myeloid leukemia(AML),as the most common type of leukemia,remains one of the leading causes of deaths fr......
CSF3R mutations were associated with an unfavorable prognosis in patients with acute myeloid leukemi
Objective Acquired cytogenetic and genetic abnormalities play essential roles in the pathogenesis and prognoses of acute......
Microarray profile of circular RNAs identifies circ-SEMA6A a new biomarker for acute myeloid leukemi
Objective Acute myeloid leukemia(AML),the most common hematopoietic malignant proliferative myeloid disorder in adults,i......
MicroRNA-29b-3p promotes chemoresistance reversion inacute myeloid leukemia partly through targeting
目的 Chemotherapy resistance frequently drives acute myeloid leukemia(AML)progression and consequently results in poor p......
FLT3-ITD with DNMT3A R882 Double-Mutation Is an Also Poor Prognostic Factor in Chinese Patients with
目的 To investigate the clinical characteristics of the AML patients with FLT3-ITD/DNMT3A double mutations and outcomes ......
A unique histone H3K4me3 genome binding pattern identified in a cancer pedigree with an MLL3 germlin
Objective Evidence suggests that alterations in histone modifications are crucial in cancer development and progression.......
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HLA-10/10 matched unrelated donor versus sibling donor hematopoietic stem cell transplantation for a
Objective To evaluate the outcomes of human leukocyte antigen(HLA)matched unrelated donor hematopoietic stem cell transp......
Study on the effect of decitabine on the proportions of MDSCs and Tregs in peripheral blood and bone
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The Prognostic Value of the Peripheral Blood Cell Counts Changes during Induction Chemotherapy in Pa
Objective Due to the clinical and genetic heterogeneity of the disease,the recurrence-free survival(RFS)and long-term su......
Reduced protocadherin17 expression in leukemia stem cells:the clinical and biological effect in acut
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Epigenetic priming with decitabine followed by low-dose idarubicin/cytarabine in high-risk myeloid n
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Identification of an allosteric small-molecule inhibitor against IDH2/R140Q for the treatment of acu
Objective Mutations in the metabolic genes contribute to the initiation and maintenance of tumors.Isocitrate dehydrogena......
Overexpression of long noncoding RNA HOXA-AS2 predicts an adverse prognosis and promotes tumorigenes
Objective Acute myeloid leukemia(AML),as a highly heterogeneous malignancy,originates from hematopoietic stem cells.It h......
Single-cell transcriptional heterogeneity suggests novel fingerprint of relapse in acute myeloid leu
Objective The heterogeneity of acute myeloid leukemia(AML)plays an important role in the development of drug resistance....
目的 The FLT3-ITD mutation is an independent risk factor for poor prognosis of acute myeloid leukemia(AML).Allogeneic he......
Exploring of Mutational Landscape and Prognostic Factors in Intermediate-Risk Cytogenetic Acute Myel
Objective Acute myeloid leukemia(AML)is a common hematologic malignance with strong heterogeneity,different cytogenetic ......
Objective AML(acute myeloid leukemia))originates from the abnormal clonal proliferation of myeloblast which often combin......
Objective It is widely accepted that leukemogenesis results from the accumulation of genetic and epigenetic alteration d......
目的 Phospholipase D1(PLD1)is a gene that encodes a phosphatidylcholine-specific phospholipase.PLD1 expression has previ......
Down-regulation of miR-29c is a prognostic biomarker in acute myeloid leukemia and can reduce the se
Objective Acute myeloid leukemia(AML)is a malignant tumor of myeloid progenitor cells.It is characterized by the rapid g......
High-dose cytarabine for consolidation therapy of acute myeloid leukemia in first complete remission
Background New evidence has questioned the role of high-dose cytarabine (HDAC) in consolidation therapy of acute myeloid......
High doses of daunorubicin during induction therapy of newly diagnosed acute myeloid leukemia: a sys
The right dose of daunorubicin (DNR) for the treatment of newly diagnosed acute myeloid leukemia (AML)is uncertain.Previ......
Effect of adding gemtuzumab ozogamicin to induction chemotherapy for newly diagnosed acute myeloid l
Background Gemtuzumab ozogamicin (GO) is a targeted antineoplastic agent comprised of a recombinant anti-CD33 humanized ......
microRNA-494 activation overcomes the drug resistance of acute myeloid leukemia cells induced by bon
Introduction Acute myeloid leukemia (AML) is a malignant and aggressive disease not sensitive to chemotherapy because me......
KRAS (G12D) cooperates with AML1/ETO to initiate a mouse model mimicking human acute myeloid leukemi
Background/Aims It has been demonstrated that KRAS mutations represent about 90% of cancer-associated mutations,and that......
Quantitative proteomic and microarray analyses of acute myeloid leukemia cell HL-60 exposed to 5-aza
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As a diverse group of malignancies and immune system functional disorders, acute myeloid leukemia (AML) is closely relat......
MicroRNA-9 Promotes Proliferation of Leukemia cells in Adult CD34 Positive Acute Myeloid Leukemia wi
Acute myeloid leukemia (AML) is a group of heterogeneous hematopoietic malignancies sustained by a small population of l......
A polymorphism in GAS5 promoter impacts efficacy of cytarabine-based chemotherapy in Chinese AML pat
OBJECTIVE SNPs in IncRNAs may alter the expression or secondary structure of IncRNAs and then impact their functions.Whe......
Prognostic analysis of acute myeloid leukemia with FLT3-ITD and DNMT3A R882 mutations after allogene
FLT3-ITD and DNMT3A R882 mutations are both independent factors for poor prognosis of acute my eloid leukemia(AML).Allog......
PURPOSE In the work, we investigate the use of support vector machines(SVM) to analyze the flow eytometry based acute my......
Unlike genetic aberrations, epigenetic alterations do not modify the DNA coding sequence, and can be reversed pharmacolo......
A rare case of acute myeloid leukemia presented with obstructive jaundice caused by bile duct monobl
Monoblastic sarcoma is the most rare form of myeloid sarcoma.We presented a case ot a 56-year-old woman with monoblastic......
Objective Somatic mutations of SF3B1 gene have recently been identified in hematopoietic malignancies.The frequency and ......
Objective MicroRNA miR-378 plays important roles in tumorigenesis by enhancing cell survival,reducing apoptosis,promotin......
FTO,the first m6A demethylase,has been associated to promote leukemogenesis and other cancers.We identified meclofenamic......
4-Hydroxyphenyl Retinamide Preferentially Targets FLT3 Mutated Acute Myeloid Leukemia via ROS Induct
FMS-like tyrosine kinase 3 (FLT3) mutation is strongly associated with poor prognosis in acute myeloid leukemia (AML).Th......
